Risk factors for palmo-plantar pustulosis in a developing country

Twenty patients with palmo-plantar pustulosis (10 males and 10 females) with a mean age of 41 +/- 6.4 years were compared to 20 controls (10 males and 10 females, mean age 42 +/- 7.2 years, for possible risk factors for palmo-plantar pustulosis. No statistically significant difference was found when the two groups were compared as regards history of atopy diabetes mellitus and thyroid disease. A statistically significant difference was found with regard to cigarette smoking (P < 0.001) and presence of joint symptoms (P < 0.01). This pattern, with minor variations, is similar to the findings in Western countries. There is a need for increased awareness of this association in developing countries. A larger population based study will be highly desirable.