Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A model for standardization of lung function parameters by height

S Kostianev1, M Ivanova

  • 1Department of Pathophysiology, University of Medicine, Plovdiv, Bulgaria.

Folia Medica
|January 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Respiratory infections in the post-COVID-19 era: impact, prevalence, and clinical characteristics of bacterial and viral co-infections.

Frontiers in medicine·2025
Same author

The genus Coelastrella (Chlorophyceae, Chlorophyta): molecular species delimitation, biotechnological potential, and description of a new species Coelastrella affinis sp. nov., based on an integrative taxonomic approach.

Antonie van Leeuwenhoek·2024
Same author

Quality Improvement in an Anaesthesiology and Intensive Care Unit Through Pain Assessment and Control.

Nigerian journal of clinical practice·2024
Same author

Baseline brain function in the preadolescents of the ABCD Study.

Nature neuroscience·2021
Same author

[STUDY OF SENSITIVITY TO ANTI-MICROBIAL AGENTS OF MICRO-ORGANISMS FROM ZONE OF PURULENT INFLAMMATION AMONG PATIENTS OF MAXILLOFACIAL HOSPITAL DEPARTMENT].

Georgian medical news·2020
Same author

[EPIGENETIC REGULATION OF ADRENAL CHROMAFFIN CELLS DEVELOPMENT (REVIEW)].

Georgian medical news·2018
Same journal

Therapeutic potential of <i>Glycyrrhiza glabra</i> (licorice) in modulating metabolic and inflammatory parameters in women with PCOS.

Folia medica·2026
Same journal

The pitfalls of gallbladder agenesis combined with small bowel malrotation.

Folia medica·2026
Same journal

Hydatid disease of the ribs: a diagnostic challenge with an endless differential diagnosis - a case report.

Folia medica·2026
Same journal

Integrative genomic analysis of missense mutations and target genes in hemorrhoid pathogenesis.

Folia medica·2026
Same journal

Clinical case of a patient with fatal development of gas gangrene while using totally implantable venous access devices.

Folia medica·2026
Same journal

Finite element analysis and photoelasticity in dental biomechanics: history, applications, comparative insights and future directions for improvement of FEA.

Folia medica·2026
See all related articles

Lung function reference values are best standardized using height-specific power functions. This study developed models for boys and men, finding age is neutralized in children but age-related variations persist in adult men.

Area of Science:

  • Pulmonary Medicine
  • Human Physiology
  • Biostatistics

Background:

  • Lung function parameters correlate strongly with individual height.
  • Accurate reference values for lung function necessitate height standardization.
  • Existing models may not fully account for age and height interactions.

Purpose of the Study:

  • To develop and validate height-standardized models for lung function parameters.
  • To investigate the influence of age and height on lung function standardization in healthy individuals.
  • To establish reliable reference equations for lung function in children and adults.

Main Methods:

  • Analysis of lung function parameters (FEV1, VC) in two healthy cohorts: boys (7-14 years) and men (30-60 years).
  • Statistical modeling using power functions to standardize lung function by height (e.g., FEV1/H^x, VC/H^y).

Related Experiment Videos

  • Correlation and residual analysis to assess model accuracy and identify age/height-related peculiarities.

    • Main Results:

    • Optimal height standardization for boys used FEV1/H^2.7 and VC/H^2.6.
    • Optimal height standardization for men used FEV1/H^2.5 and VC/H^2.4.
    • The model for children effectively neutralized age, while adult men showed age-related variations and heteroscedasticity.

    Conclusions:

    • Height-specific power functions provide effective standardization for lung function parameters.
    • The developed models offer improved reference equations, particularly for children.
    • Further research may be needed to fully address age-related variations in adult lung function standardization.