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In vitro activity of premafloxacin, a new extended-spectrum fluoroquinolone, against pathogens of veterinary
J L Watts1, S A Salmon, M S Sanchez
1Animal Health Discovery Research, Pharmacia & Upjohn, Inc., Kalamazoo, Michigan 49001, USA. jlwatts@am.pnu.com
Antimicrobial Agents and Chemotherapy
|May 1, 1997
Abstract:
The in vitro activity of premafloxacin against 673 veterinary pathogens was evaluated. Premafloxacin was equivalent to ciprofloxacin, enrofloxacin, and danofloxacin in activity against the gram-negative bacilli but was much more active (MIC for 90% of the strains tested [MIC90], 0.015 to 0.25 microg/ml) than the comparison antimicrobial agents (MIC90, 0.13 to 16.0 microg/ml) against the staphylococci, streptococci, and anaerobes tested.