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Further evidence of genetic heterogeneity in hereditary hydronephrosis
D McHale1, M E Porteous, J Wentzel
1Yorkshire Regional Genetics Service, St. James Hospital, Leeds, UK.
Clinical Genetics
|December 1, 1996
Abstract:
Hereditary hydronephrosis is a rare condition but several families are described in the literature. The inheritance pattern is autosomal dominant (McKusick number 143400) but the exact aetiology of the hydronephrosis is not clear. However, linkage with the HLA region on chromosome six has been shown previously. We report a family not showing linkage to this region, giving further evidence of genetic heterogeneity in this condition.