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Updated: Jul 29, 2026
A Novel Method: Super-selective Adrenal Venous Sampling
Published on: September 15, 2017
[Spontaneous retroperitoneal hematoma in adrenal metastasis]
History And Clinical Findings:
A 58-year-old man was hospitalized because of acute dull upper abdominal pain, radiating into the right flank and lower abdomen. The past history was unremarkable expect for thyroidectomy, performed 30 years previously for thyroid carcinoma. There was painful resistance on palpation of the right upper abdomen. The patient had not recently sustained any trauma. BIOCHEMICAL AND IMAGING INVESTIGATIONS: Erythrocyte sedimentation rate was increased to 38 mm/h, haemoglobin concentration was 11.7 g/dl but fell to 9.9 g/dl within the first 24 hours. Ultrasound and computed tomography (CT) revealed a large retroperitoneal mass (5 x 6.5 x 15 cm), its density of 64 Hounsfield units most strongly suggesting an haematoma. CT also showed enlargement of the right adrenal. Chest radiography demonstrated a space-occupying lesion in the right upper lobe.
Diagnosis, Treatment And Course:
As a retroperitoneal haematoma of uncertain aetiology was suspected, a laparotomy was performed. The haematoma was evacuated and the adrenal, showing tumours changes, was excised. Histologically it was a mucocellular metastasis. The chest radiograph suggested carcinoma of the lung as the primary. The illness took a rapidly fatal course. Autopsy confirmed a poorly differentiated adenocarcinoma of the lung.
Conclusion:
Trauma or anticoagulation should be considered first in the differential diagnosis of retroperitoneal haematoma of uncertain aetiology. However, adrenal metastasis should be thought of as a rare possibility.
