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[Insulinoma. Clinical and surgical considerations concerning a case]
O Porzio1, G Rossi, A Biscardi
1Reparto di Chirurgia d'Urgenza, USL RM 7, Ospedale S. Eugenio, Roma.
Minerva Chirurgica
|March 1, 1997
Summary
Insulinoma, a rare pancreatic tumor, can cause hypoglycemia. Surgical removal of this benign tumor led to complete recovery in a patient with atypical symptoms.
Area of Science:
- Endocrinology
- Surgical Oncology
- Gastroenterology
Background:
- Insulinoma is the most common pancreatic endocrine tumor, originating from beta-islet cells.
- It autonomously secretes insulin, leading to spontaneous hypoglycemia and characteristic symptoms.
- Insulinomas are rare, with an incidence of 0.5 per million annually, and up to 90% are benign and solitary.
Observation:
- The study reviewed international research on insulinoma over 20 years.
- A case presented a large insulinoma in the pancreatic body and tail with atypical psychic symptoms.
- Surgical intervention involved distal pancreatectomy with splenectomy.
Findings:
- Up to 90% of insulinomas are benign and solitary, affecting all age groups.
- The patient experienced complete recovery post-surgery, with normalized glucose and insulin levels.
- No surgical complications were noted during the postoperative period.
Implications:
- Surgical resection is an effective treatment for insulinoma.
- Complete tumor removal can resolve hypoglycemia and associated symptoms.
- Early diagnosis and surgical management are crucial for favorable patient outcomes.