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Related Experiment Videos

Sex differences in corticosteroids in man

M Schöneshöfer, G G Wagner

    The Journal of Clinical Endocrinology and Metabolism
    |October 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    This study measured serum steroid concentrations in men and women across the menstrual cycle. Women in the follicular phase had significantly lower levels of most steroids compared to men and women in the luteal phase.

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    [Saving motives in young, middle-aged, and older adults. Preliminary results of a new inventory for exploring lifespan saving motives].

    Zeitschrift fur Gerontologie und Geriatrie·2012

    Area of Science:

    • Endocrinology
    • Reproductive Biology
    • Steroid Biochemistry

    Background:

    • Hormonal fluctuations significantly impact female physiology.
    • Understanding baseline steroid levels is crucial for interpreting endocrine function.

    Purpose of the Study:

    • To quantify serum concentrations of key steroid hormones.
    • To compare these levels between normal men and women in different menstrual cycle phases.

    Main Methods:

    • Radioimmunoassay (RIA) was used for simultaneous quantification of multiple steroids.
    • Serum samples were collected from 18 men, 14 women (follicular phase), and 14 women (luteal phase).

    Main Results:

    • Women in the follicular phase showed significantly lower 17-hydroxyprogesterone, deoxycorticosterone, corticosterone, and aldosterone than men.

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  • Follicular phase women also had lower levels of these steroids compared to luteal phase women.
  • Progesterone levels did not differ significantly between follicular phase women and men.

    • Conclusions:

    • Menstrual cycle phase significantly influences serum steroid profiles in women.
    • Steroid levels in follicular phase women are generally lower than in men and luteal phase women, except for progesterone.