Related Experiment Videos
Cutaneous necrotizing vasculitis associated with hepatitis A virus infection
J Press1, S Maslovitz, I Avinoach
1Pediatric Emergency Room, Soroka Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
The Journal of Rheumatology
|May 1, 1997
Summary
Hepatitis A infection can cause cutaneous necrotizing vasculitis in children. This case report details a young girl who recovered after treatment, highlighting viral causes of vasculitis.
Area of Science:
- Pediatric Rheumatology
- Infectious Diseases
- Dermatology
Background:
- Hepatitis A virus (HAV) is a rare cause of cutaneous necrotizing vasculitis (CNV) in adults.
- CNV is an inflammatory condition affecting blood vessels, leading to skin necrosis.
Observation:
- A 2-year-old girl presented with CNV during the acute phase of hepatitis A infection.
- Skin biopsy confirmed necrotizing vasculitis involving superficial and deep blood vessels with fibrin thrombi.
Findings:
- The patient received a 5-week course of corticosteroids.
- Serum liver enzymes normalized within 6 weeks, and skin lesions healed with scarring.
Implications:
- Hepatitis A should be considered as a potential viral trigger for CNV in children.
- This case expands the understanding of viral-associated vasculitis in pediatric populations.