A microdrive for use with glass or metal microelectrodes in recording from freely-moving rats

A new subminiature microdrive assembly is described for electrophysiological recording from behaving rats. This very small, lightweight system allows excellent precision in electrode placement and can maintain stable recordings over extended periods. Since the electrode is nonrotating, tissue damage is minimized. Either metal or glass microelectrodes may be used with the system, offering the possibility of iontophoresis for cell marking or neuropharmacological manipulations.