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Related Concept Videos

Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
The Functions of the Skeletal System01:22

The Functions of the Skeletal System

The most apparent functions of the skeletal system are support, protection, and movement. However, bone tissue also performs several other critical metabolic functions. For one, the bone matrix acts as a reservoir for a number of minerals important to the functioning of the body, especially calcium and phosphorus. These minerals, present in the bone tissue, can be released back into the bloodstream when required. Calcium ions, for example, are essential for muscle contractions and controlling...
Bone Disorders01:29

Bone Disorders

Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Disorders of the Skeletal Muscle01:28

Disorders of the Skeletal Muscle

The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...

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Related Experiment Video

Updated: Jul 26, 2026

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
07:56

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts

Published on: January 29, 2018

Skin and bones: dermatologic conditions with skeletal abnormalities

C L Harlow1, R F Kilcoyne, J Aeling

  • 1Department of Radiology, University of Colorado Health Sciences Center, Denver 80262, USA.

Skeletal Radiology
|April 1, 1997
PubMed
Summary

Many skin conditions are linked to skeletal abnormalities. This review highlights these associations to improve radiologist awareness of dermatologic conditions and their bone manifestations.

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Area of Science:

  • Radiology
  • Dermatology
  • Skeletal Abnormalities

Background:

  • Dermatologic conditions can present with associated skeletal abnormalities.
  • Radiologists require knowledge of these connections for accurate diagnosis.

Purpose of the Study:

  • To educate radiologists on the link between skin and bone conditions.
  • To provide a comprehensive overview of dermatologic disorders with skeletal manifestations.

Main Methods:

  • A pictorial essay format was used.
  • Twenty-four specific skin and bone conditions were analyzed.
  • Conditions were categorized by affected skin layer or type (epidermis, dermis, sebaceous glands, pigmentation, nails, tumors, phakomatoses, immunologic-allergic disorders, infections).

Main Results:

  • The essay details numerous dermatologic conditions with associated skeletal abnormalities.
  • A table is included for an expanded list of these associations.
  • Visual examples and discussions are provided for each condition.

Conclusions:

  • This resource aims to increase familiarity with dermatologic conditions and their skeletal counterparts.
  • Enhanced awareness can lead to improved diagnostic accuracy in radiology.
  • Practitioners will benefit from understanding these interdisciplinary connections.