Related Experiment Videos
Chlorhexidine spray effects on plaque accumulation in developmentally disabled patients
R Steelman1, D Holmes, M Hamilton
1Department of Pediatrics, West Virginia University, Morgantown 26506, USA.
The Journal of Clinical Pediatric Dentistry
|July 1, 1996
Summary
This study found that both 0.12% and 0.06% chlorhexidine gluconate sprays effectively reduce plaque in developmentally disabled patients. Lower concentrations (0.06%) are as effective as higher ones (0.12%) for plaque control.
Area of Science:
- Oral Health
- Pharmacology
- Developmental Disabilities
Background:
- Chlorhexidine gluconate is used to reduce plaque in developmentally disabled patients.
- Standard oral hygiene may be insufficient for effective plaque control in this population.
Purpose of the Study:
- To compare the efficacy of two chlorhexidine gluconate spray concentrations (0.12% and 0.06%) in reducing plaque accumulation.
- To evaluate chlorhexidine gluconate as an adjunct to standard oral hygiene in developmentally disabled individuals.
Main Methods:
- A double-blind crossover study involving 8 developmentally disabled patients (ages 12-33).
- Participants received twice-daily chlorhexidine gluconate spray (0.12% or 0.06%) for 30 days, followed by alternating concentrations for another 30 days.
- Plaque indices were measured, with standard oral hygiene maintained throughout.
Main Results:
- Both 0.12% and 0.06% chlorhexidine gluconate sprays significantly reduced plaque accumulation.
- No statistically significant difference in plaque reduction was observed between the 0.12% and 0.06% concentrations.
Conclusions:
- A 0.06% chlorhexidine gluconate spray concentration is as effective as a 0.12% concentration for reducing plaque.
- Lower concentrations of chlorhexidine gluconate may be a viable option for plaque control in developmentally disabled patients.