Related Experiment Video
Updated: Aug 14, 2026

A Mouse Model of Lumbar Spine Instability
Published on: April 23, 2021
Anatomic considerations of the lumbar isthmus
1Department of Orthopaedic Surgery, Medical College of Ohio, Toledo, USA.
Study Design:
A morphometric study of lumbar isthmus from L1 to L5 on 30 dried lumbar spines was conducted.
Objective:
To provide anatomic data about the lumbar isthmus and to quantitatively evaluate structural features of the lumbar isthmus and its relationship to adjacent anatomic structures.
Summary Of Background Data:
There are very few anatomic studies about the lumbar isthmus, and no study describes the relationship of the lumbar isthmus to its adjacent structures.
Methods:
Direct measurements using digital calipers and a goniometer were taken from 30 dried lumbar spines. Anatomic evaluation focused on the lumbar isthmus and its related structures, the isthmus pedicle, and superior and inferior facets. Seven linear and four angular parameters of the lumbar isthmus were determined.
Results:
The length of the superior edge of the isthmus gradually increased from L2 to L5 (from 8.22 +/- 1.43 mm at L2 to 10.44 +/- 1.90 mm at L5), and that of its inferior edge progressively decreased from L2 to L5 (from 8.67 +/- 1.76 mm at L2 to 6.34 +/- 1.74 mm at L5). The superoinferior diameter of the isthmus decreased from L3 to L5 (from 13.87 +/- 1.77 mm at L3 to 13.26 +/- 2.49 mm at L5). The superior edge of the isthmus was the thinnest at L4 (1.62 +/- 0.58 mm), and its thickness inferiorly increased from L1 to L5 (from 6.71 +/- 1.47 mm at L1 to 7.76 +/- 1.08 mm at L5). The medial and caudal inclination of the isthmus with respect to the pedicle gradually increased from L1 to L5 (from 112.3 degrees +/- 13.8 degrees at L1 to 119.2 degrees +/- 11.2 degrees at L5 medial inclination and from 132.5 degrees +/- 8.8 degrees at L2 to 139.0 degrees +/- 12.1 degrees at L5 caudal inclination, respectively). The dimensions of the lumbar isthmus were positively correlated to dimensions of the pedicle and orientations of the facets.
Conclusions:
This study provides detailed anatomic data of the lumbar isthmus. Anatomic parameters of the lumbar isthmus are related to the vertebral levels and have a significant correlation with the angles of the facets and the dimensions of the pedicles. The vulnerability of the pars interarticularis of the fifth lumbar vertebra has been anatomically confirmed.
Related Concept Videos
Abdominal Regions and Quadrants
The simpler quadrants approach, which is more commonly used in medicine, subdivides the cavity with one horizontal and one vertical line that intersects at the patient's umbilicus (navel). The four quadrants...
Muscles of the Abdomen
Anterolateral Region
The anterolateral region comprises five paired muscles classified into the lateral and anterior...
Abdominal Aorta
The celiac trunk, a singular artery, divides into the left gastric artery, which...
Histology of the Small Intestine
The intestinal lining features transverse folds called circular folds, each housing fingerlike projections known as intestinal villi. These villi are covered by a layer of simple columnar epithelium, also referred to as...
Large Intestine
The ileocecal sphincter, a mucous membrane fold, guards the opening from the ileum to the large intestine. This valve permits material from the small intestine to pass into the large intestine. Attached to the ileocecal valve is the cecum. This small pouch, approximately 6 cm long, has a twisted, coiled tube known as...
Herniated Intervertebral Disc l: Introduction

