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The GCMS analysis of tranylcypromine (Parnate) in a suspected overdose
1Saint Louis University Medical School, Department of Pathology, Berkeley, Missouri 63134, USA.
Forensic Science International
|April 18, 1997
Abstract:
A fatal overdose involving tranylcypromine (Parnate) where blood, urine and tissues were quantitated using a pentafluoroproprionic anhydride (PFPA) derivative and gas-chromatography/mass spectroscopy (GCMS). The samples were re-quantified over several weeks demonstrating a significant loss of drug in tissues but not blood or urine specimens. The urine was positive for methamphetamine which has been a suspected metabolite.