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Imaging of maxillary osteoradionecrosis

W C Peh1, J S Sham

  • 1Department of Diagnostic Radiology, University of Hong Kong, Queen Mary Hospital, Hong Kong.

Australasian Radiology
|May 1, 1997
PubMed
Summary

Maxillary osteoradionecrosis, a radiotherapy complication for nasopharyngeal carcinoma, occurred in 0.8% of patients. Dental issues and multiple radiotherapy courses were identified as key risk factors.

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Area of Science:

  • Oncology
  • Radiotherapy
  • Maxillofacial Surgery

Background:

  • Nasopharyngeal carcinoma (NPC) treatment often involves radiotherapy.
  • Osteoradionecrosis (ORN) is a potential complication of head and neck radiotherapy.
  • Maxillary ORN can significantly impact patient quality of life.

Purpose of the Study:

  • To determine the incidence of maxillary osteoradionecrosis in NPC patients.
  • To identify risk factors associated with maxillary osteoradionecrosis.
  • To evaluate the utility of CT scans in diagnosing and monitoring maxillary ORN.

Main Methods:

  • Retrospective case review over a 3-year period.
  • Analysis of patient data from Queen Mary Hospital, Hong Kong.
  • Serial computed tomography (CT) scans (axial and coronal planes) were utilized.

Main Results:

  • Four cases of maxillary osteoradionecrosis were diagnosed, yielding an incidence of 0.8%.
  • Mean time to presentation was 34 months post-radiotherapy.
  • Identified risk factors included dental problems and multiple radiotherapy courses.
  • CT scans effectively demonstrated bony sclerosis, antral wall destruction, and aided in excluding tumor recurrence.

Conclusions:

  • Maxillary osteoradionecrosis is a rare but significant complication following radiotherapy for nasopharyngeal carcinoma.
  • Dental health and cumulative radiotherapy doses are critical risk factors.
  • Serial CT imaging is a valuable tool for the diagnosis and management of maxillary ORN.

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