Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Skeletal metastases

T Möller1

  • 1Oncology Center, Lund, Sweden.

Acta Oncologica (Stockholm, Sweden)
|January 1, 1996
PubMed
Summary
This summary is machine-generated.

Radiotherapy effectively palliates pain from skeletal metastases with minimal side effects. Further research is needed to establish optimal dosing and understand pain relief mechanisms.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Heat-treatment-induced enhancement of activity and stability in Rh/Mo-doped PtNi octahedra for the oxygen reduction reaction.

Nanoscale·2025
Same author

Proof-of-concept of a prior validated LC-MS/MS method for detection of <i>N</i>-lactoyl-phenylalanine in dried blood spots before, during and after a performance diagnostic test of junior squad triathletes.

Frontiers in sports and active living·2025
Same author

[Sustainability in Outpatient Pulmonary Rehabilitation in Patients with Asbestosis - Results of an 8-Year Follow Up].

Pneumologie (Stuttgart, Germany)·2020
Same author

Ultrafast relaxation of photoexcited superfluid He nanodroplets.

Nature communications·2020
Same author

[Preconditioning of the lungs and circulation before visceral and thoracic surgical interventions].

Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen·2019
Same author

A prospective, clinical, nonrandomized controlled trial of individualized, nurse-led patient-centred intervention in patients with psoriasis.

The British journal of dermatology·2018
Same journal

Overall survival following palliative immune checkpoint inhibitor treatment according to ECOG performance status: a large registry-based study.

Acta oncologica (Stockholm, Sweden)·2026
Same journal

Pathological characteristics and prognosis of very young patients with early breast cancer: a comparative analysis with older patients.

Acta oncologica (Stockholm, Sweden)·2026
Same journal

Recent survival trends in the most fatal cancers in the Nordic countries: gains in some but not in all.

Acta oncologica (Stockholm, Sweden)·2026
Same journal

First-in-human quantitative [¹⁵O]H₂O PET imaging of tumour blood flow at rest and during exercise in lymphoma patients.

Acta oncologica (Stockholm, Sweden)·2026
Same journal

Starshot field configuration in the linac isocentre size determination: a comparison of film and electronic portal imaging device measurements.

Acta oncologica (Stockholm, Sweden)·2026
Same journal

Perspectives on artificial intelligence-generated chronic disease risk predictions in early breast cancer: an international survey among radiation oncologists.

Acta oncologica (Stockholm, Sweden)·2026
See all related articles

Area of Science:

  • Oncology
  • Radiology
  • Palliative Care

Background:

  • Skeletal metastases frequently cause significant pain.
  • Radiotherapy is a common treatment for pain palliation.
  • Mechanisms of radiotherapy-induced pain relief are not fully understood.

Purpose of the Study:

  • To synthesize current literature on radiotherapy for skeletal metastases.
  • To evaluate the efficacy and safety of various radiotherapy modalities.
  • To identify areas for future research in skeletal metastasis radiotherapy.

Main Methods:

  • Literature synthesis based on 171 scientific articles.
  • Included randomized, prospective, and retrospective studies.
  • Analysis of data from 13,054 patients.

Related Experiment Videos

Main Results:

  • Radiotherapy achieves pain freedom or substantial alleviation in nearly all cases with few side effects.
  • Half-body irradiation is effective for multiple metastatic sites.
  • Systemic radiotherapy with radionuclides may benefit generalized skeletal pain.
  • Early radiotherapy for spinal cord compression can prevent symptom worsening.

Conclusions:

  • Radiotherapy is a highly effective palliative treatment for skeletal metastases.
  • Half-body irradiation and systemic radionuclide therapy are valuable options.
  • Further research is required to optimize dose fractionation and evaluate fracture prevention/healing roles.