Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Human gene therapy for lung cancer]

T Fujiwara1, F Inoue, N Tanaka

  • 1First Department of Surgery, Okayama University Medical School.

Nihon Rinsho. Japanese Journal of Clinical Medicine
|May 1, 1997
PubMed
Summary

Gene therapy offers a new strategy for treating lung cancer by targeting genetic alterations. This approach aims to inhibit oncogenes or replace tumor suppressor genes, potentially improving outcomes for this deadly disease.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Monodomain Blue Phase Liquid Crystal Layers for Phase Modulation.

Scientific reports·2017
Same author

Efficacy and safety of live varicella zoster vaccine in diabetes: a randomized, double-blind, placebo-controlled trial.

Diabetic medicine : a journal of the British Diabetic Association·2015
Same author

New multilocus sequence typing of MRSA in São Paulo, Brazil.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas·2011
Same author

Various costimulatory pathways are essential for induction of regulatory cells by intratracheal delivery of alloantigen.

Transplantation proceedings·2005
Same author

Syenergistic effect of 15-deoxyspergualin with costimulation blockade on alloimmune response.

Transplantation proceedings·2004
Same author

Interstitial pneumonia associated with autoimmune pancreatitis.

Gut·2004

Area of Science:

  • Oncology
  • Molecular Biology
  • Genetics

Context:

  • Lung cancer remains a leading cause of cancer mortality globally.
  • Current therapeutic strategies for lung cancer lack standardization, contributing to high mortality rates.
  • Multistep genetic alterations are recognized as key drivers in human lung cancer development.

Purpose:

  • To review recent advancements in gene therapy for human lung cancer.
  • To explore novel gene therapeutic strategies utilizing recombinant viral vectors.
  • To discuss methods for inhibiting oncogene expression or replacing tumor suppressor genes.

Summary:

  • Human gene therapy is advancing, with effective gene delivery techniques now available.
  • Recombinant, replication-defective viral vectors are proposed for lung cancer gene therapy.
  • The strategy involves targeting specific genetic alterations, including oncogenes and tumor suppressor genes.

Impact:

  • Gene therapy presents a promising new avenue for lung cancer treatment.
  • This approach could lead to more effective and targeted therapies for lung cancer patients.
  • Further clinical evaluation of gene therapy is crucial for its integration into standard care.

Related Experiment Videos