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Endometrial ossification in a postmenopausal woman

M Shimizu1, M Nakayama

  • 1Department of Pathology, Kawasaki Medical School, Okayama, Japan.

Journal of Clinical Pathology
|February 1, 1997
PubMed
Summary

Endometrial ossification, the presence of bone in the uterine lining, is rare in postmenopausal women. This case highlights its potential to mimic intrauterine foreign bodies on ultrasound and avoid misdiagnosis of malignancy.

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Area of Science:

  • Gynecology
  • Pathology
  • Radiology

Background:

  • Endometrial ossification is a rare condition characterized by the presence of mature bone within the uterine lining.
  • It is typically seen in younger women (20-40 years old) and is uncommon in postmenopausal individuals.

Observation:

  • A 62-year-old woman presented with increased vaginal discharge.
  • Transvaginal ultrasonography revealed a hyperechoic area in the uterine cavity, resembling an intrauterine foreign body.
  • Histological examination of endometrial curettage confirmed mature bone with neutrophilic infiltration, with no signs of malignancy.

Findings:

  • The case presents a rare instance of endometrial ossification in a postmenopausal woman.
  • Ultrasonographic findings mimicked an intrauterine foreign body, necessitating careful evaluation.

Implications:

  • Clinicians should consider endometrial ossification in the differential diagnosis of intrauterine foreign bodies on ultrasound, even in older patients.
  • Pathologists must be aware of this rare entity to prevent misdiagnosis as a malignant mixed müllerian tumor, thus avoiding unnecessary hysterectomy.

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