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Stereotactic multiple are radiotherapy. IV--Haemangioblastoma
P R Chakraborti1, K B Chakrabarti, D Doughty
1Department of Radiotherapy and Clinical Oncology, St. Bartholomew's Hospital, London, UK.
British Journal of Neurosurgery
|April 1, 1997
Summary
Radiotherapy, including radiosurgery, is an effective treatment for haemangioblastoma, with high response rates and no observed complications. This approach offers a focused option for discrete lesions and can be combined with conventional radiotherapy for complex cases like von Hipple-Lindau syndrome.
Area of Science:
- Neurosurgery
- Radiation Oncology
Background:
- Haemangioblastomas are rare tumors requiring effective treatment strategies.
- Conventional external beam radiotherapy and stereotactic radiotherapy (radiosurgery) are established modalities.
Observation:
- Six haemangioblastomas in five patients were treated and followed for a mean of 40 months.
- Five lesions were treated with radiosurgery, achieving four complete radiological responses and one static response.
- One lesion near critical structures was treated with conventional radiotherapy, showing a partial response.
Findings:
- Radiotherapy, particularly radiosurgery, demonstrated significant efficacy in treating haemangioblastomas.
- Neurological symptoms and signs improved in patients receiving radiotherapy.
- No complications were reported in the treated patient cohort.
Implications:
- Radiotherapy is a viable and effective treatment option for haemangioblastomas, complementing existing literature.
- Stereotactic radiosurgery is well-suited for discrete haemangioblastomas due to its focused nature.
- A combined approach of conventional radiotherapy followed by radiosurgery may be beneficial for managing multiple or metachronous cerebellar haemangioblastomas in von Hipple-Lindau syndrome.