Related Experiment Videos
Elevated serum angiotensin converting enzyme levels in metastatic ovarian dysgerminoma
T P Cotter1, N P Kealy, P F Duggan
1Cork University Hospital, Ireland.
Respiratory Medicine
|April 1, 1997
Abstract:
A case of a 32-year-old XY genotype female is described, presenting with mediastinal and abdominal lymphadenopathy and associated with an elevated serum angiotensin I converting enzyme (SACE) level. Lymph node histology showed a malignant dysgerminoma of ovarian origin. Combined chemotherapy led to a radiological regression of the lymphadenopathy and coincided with a decrease in SACE concentration. The authors suggest that SACE may be a marker for disseminated germinoma tumours and may be useful for monitoring treatment.