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Nucleotide sequence, chromosome localization, and evolutionary conservation of a serine
1Department of Psychiatry, University of Iowa College of Medicine, Iowa City 52242-1000, USA.
Human Heredity
|May 1, 1997
Abstract:
The nucleotide sequence and chromosomal localization of a human pseudogene is reported. Sequence data suggest that this pseudogene was derived via reverse transcription from the gene encoding the cytosolic isoform of the enzyme serine hydroxymethyltransferase. In addition, a heteroduplex analysis of this pseudogene among several species of nonhuman primate indicates a relatively high degree of sequence conservation.