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Updated: Aug 9, 2026

Direct Mouse Trauma/Burn Model of Heterotopic Ossification
Published on: August 6, 2015
Brain heterotopia: choristoma of the back
M T Downing1, A B Hamoudi, G E Besner
1Department of Surgery, Children's Hospital, 700 Children's Drive, Columbus, OH 43 205, USA.
Abstract:
Heterotopic brain tissue, except in the head and neck region, is exceedingly rare. Mature neural tissue unexpectedly found in the subcutaneous tissues of the back of a toddler lacked an attachment to the central nervous system (CNS), and appeared to be unorganized glial tissue on pathologic evaluation. Appropriate clinical management of such lesions includes a suspicion of subcutaneous lesions near the CNS and evaluation to eliminate the presence of communication with the CNS, followed by surgical excision.

