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Cholelithiasis in early infancy

D T Wilcox1, D Casson, J Bowen

  • 1Royal Manchester Children's Hospital, Hospital Road, Manchester, M 27 1 HA, UK.

Insights

Gallstones causing obstructive jaundice in infants are rare but treatable. Surgical removal of gallstones (cholecystectomy) and common bile duct exploration were successful in three young children.

Area of Science:

  • Pediatric Surgery
  • Gastroenterology
  • Neonatal Medicine

Background:

  • Gallstones are uncommon in pediatric populations.
  • Obstructive jaundice in infants can have various etiologies.
  • Identifying predisposing factors is crucial for early diagnosis.

Observation:

  • Three infants, aged 7 weeks to 5 months, presented with obstructive jaundice.
  • Gallstones were identified as the cause of the obstruction.
  • Escherichia coli sepsis and furosemide therapy were noted risk factors in two cases.

Findings:

  • All three patients underwent successful cholecystectomy.
  • Exploration of the common bile duct was performed in all cases.
  • Surgical intervention resolved the obstructive jaundice.

Implications:

  • This case series highlights the possibility of gallstone-induced obstructive jaundice in young infants.
  • Early recognition and surgical management are effective treatment strategies.
  • Understanding risk factors like sepsis and certain medications can aid in identifying at-risk infants.

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