[Renal protective effects of calcium antagonists]

Calcium antagonists (C-A) induce different, renal hemodynamic alterations. They reduce afferent arteriolar resistance and do not change glomerular filtration rate. C-A prevent acute renal failure, especially after kidney transplantation. Calcium antagonists decrease nephrotoxicity of cyclosporine and radiocontrast media. C-A are recommended in the therapy of renovascular hypertension.