External leg compression in the treatment of vascular disease

In summary, external compression of the limbs is a mode of therapy that has enjoyed a long history in the treatment of venous and arterial disease. Evidence suggests that its beneficial effects are mediated through enhancement of venous and arterial blood flow, promotion of vasodilation, enhancement of fibrinolysis, and, in the case of obstructive arterial disease, promotion of the development of collateral circulation. The utility of external leg compression in the prevention of deep venous thrombosis and in the management of chronic venous stasis disease has been well documented, and it has become an accepted treatment for these disorders. The use of pneumatic compression in the treatment of atherosclerotic peripheral vascular and cardiovascular disease is less widespread and its indications are less well defined. Though the work of a few investigators in each of these areas shows striking benefits of the technique, further investigation in these areas is warranted. Potential benefits to patients of external limb compression therapy include its non-invasive nature, its ability to be applied in an out-patient setting, and long-term cost savings through possible avoidance of hospitalization and invasive procedures.