Age-related alterations in cardiac lysosomes

C2K77 ELISA detects cleavage of type II collagen by cathepsin K in equine articular cartilage.

Osteoarthritis and cartilage·2017

Early cathepsin K degradation of type II collagen in vitro and in vivo in articular cartilage.

Osteoarthritis and cartilage·2016

Changes in gene expression associated with matrix turnover, chondrocyte proliferation and hypertrophy in the bovine growth plate.

Acta naturae·2014

Relationship between pre-radiographic cartilage damage following anterior cruciate ligament injury and biomarkers of cartilage turnover in clinical practice: a cross-sectional observational study.

Osteoarthritis and cartilage·2013

Application of biomarkers in the development of drugs intended for the treatment of osteoarthritis.

Osteoarthritis and cartilage·2011

Serum cartilage oligomeric matrix protein (COMP) level is a marker of disease activity in relapsing polychondritis.

Clinical and experimental rheumatology·2010

PP2Acα regulates the Hippo-YAP signaling axis to promote cardiac regeneration and alleviate myocardial infarction.

Journal of molecular and cellular cardiology·2026

TMEM175 deficiency impairs autophagic degradation and alleviates mitochondrial oxidative damage in cardiomyocytes through AMPK activation.

Journal of molecular and cellular cardiology·2026

Gfpt2 modulates fibroblast activation by glutathione metabolism.

Journal of molecular and cellular cardiology·2026

Loss of Miro1 drives cardiac and mitochondrial dysfunction exacerbated by metabolic stress.

Journal of molecular and cellular cardiology·2026

Cardiometabolic stress induces HFpEF with impaired bioenergetics and disrupted proteostasis in aged female mice.

Journal of molecular and cellular cardiology·2026

Computational models show that functional remodeling, not anatomy, reshapes physiological determinants of cardiac performance in hypertrophic cardiomyopathy.

Journal of molecular and cellular cardiology·2026

Ornaments evolve faster than weapons.

Proceedings. Biological sciences·2026

Identification of ATG genes in the noble scallop Chlamys nobilis reveals unique expression strategies against low-temperature and Vibrio parahaemolyticus challenge.

Developmental and comparative immunology·2026

Interplay Between Species Traits, Community and Environmental Context Governs Temporal Stability in Riverine Fish Populations.

Ecology letters·2026

Mendelian randomization investigation into testosterone's trade-offs between longevity and reproductive fitness.

The aging male : the official journal of the International Society for the Study of the Aging Male·2026

The over-designed limb: Skeletal robustness and locomotor adaptation in terrestrial and freshwater turtles.

Journal of anatomy·2026

Total arch replacement for nondissecting aortic arch aneurysms: Risk stratification and long-term outcomes.

JTCVS open·2026

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Age-related alterations in cardiac lysosomes

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C2K77 ELISA detects cleavage of type II collagen by cathepsin K in equine articular cartilage.

Early cathepsin K degradation of type II collagen in vitro and in vivo in articular cartilage.

Changes in gene expression associated with matrix turnover, chondrocyte proliferation and hypertrophy in the bovine growth plate.

Relationship between pre-radiographic cartilage damage following anterior cruciate ligament injury and biomarkers of cartilage turnover in clinical practice: a cross-sectional observational study.

Application of biomarkers in the development of drugs intended for the treatment of osteoarthritis.

Serum cartilage oligomeric matrix protein (COMP) level is a marker of disease activity in relapsing polychondritis.

PP2Acα regulates the Hippo-YAP signaling axis to promote cardiac regeneration and alleviate myocardial infarction.

TMEM175 deficiency impairs autophagic degradation and alleviates mitochondrial oxidative damage in cardiomyocytes through AMPK activation.

Gfpt2 modulates fibroblast activation by glutathione metabolism.

Loss of Miro1 drives cardiac and mitochondrial dysfunction exacerbated by metabolic stress.

Cardiometabolic stress induces HFpEF with impaired bioenergetics and disrupted proteostasis in aged female mice.

Computational models show that functional remodeling, not anatomy, reshapes physiological determinants of cardiac performance in hypertrophic cardiomyopathy.

Ornaments evolve faster than weapons.

Identification of ATG genes in the noble scallop Chlamys nobilis reveals unique expression strategies against low-temperature and Vibrio parahaemolyticus challenge.

Interplay Between Species Traits, Community and Environmental Context Governs Temporal Stability in Riverine Fish Populations.

Mendelian randomization investigation into testosterone's trade-offs between longevity and reproductive fitness.

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Age-related alterations in cardiac lysosomes

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