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Germinal centers: a second childhood for lymphocytes

D Tarlinton1

  • 1Walter and Eliza Hall Institute of Medical Research, Royal Melbourne Hospital, Victoria 3050, Australia.

Current Biology : CB
|March 1, 1997
PubMed

Recent observations show that, in the peripheral lymphoid organs known as germinal centers, lymphocytes appear to regain the phenotypic and molecular traits of immature cells; this cellular regression may play an important role in the affinity maturation of immune responses.

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