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Absence of human herpesvirus 8 genomes in coronary atherosclerosis in immunocompetent patients
D Ye1, T C Nichols, G J Dehmer
1Department of Medicine, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, USA.
The American Journal of Cardiology
|May 1, 1997
Abstract:
Human herpevirus 8 (HHV8) has been localized to the endothelial and spindle cells of KS, suggesting a role for HHV8 in atherosclerosis. None of the 38 coronary atherectomy specimens contained HHV8 with both sensitive nested PCR assays, making it unlikely that persistent viral infection with HHV8 plays a role in coronary atherogenesis in the general population of the United States.