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Liver transplantation after coronary artery bypass grafting
F Pelosi1, G B Klintmalm, W B Simon
1Baylor Cardiovascular Institute, Department of Internal Medicine, Baylor University Medical Center, Dallas, Texas 75246, USA.
The American Journal of Cardiology
|May 15, 1997
Insights
Liver transplantation was performed in twelve patients post-coronary artery bypass grafting (CABG). Most developed hepatitis C liver disease from transfusions during CABG surgery.
Area of Science:
- Cardiology
- Hepatology
- Transplantation
Background:
- Coronary artery bypass grafting (CABG) is a common cardiovascular procedure.
- Hepatitis C virus (HCV) infection can lead to severe liver disease.
- Blood transfusions during surgery carry a risk of viral transmission.
Purpose of the Study:
- To describe outcomes of liver transplantation in patients with prior CABG.
- To investigate the etiology of liver disease in this patient cohort.
Main Methods:
- Retrospective case series of twelve patients.
- Review of medical records for patients undergoing liver transplantation after CABG.
Main Results:
- All twelve patients underwent liver transplantation following CABG.
- Hepatitis C infection was the primary cause of liver disease in most patients.
- HCV infection was linked to blood transfusions received during the initial CABG procedure.
Conclusions:
- Liver transplantation is a viable option for patients with end-stage liver disease post-CABG.
- Hepatitis C transmission via blood transfusion during CABG can necessitate future liver transplantation.
Abstract:
Twelve patients are described who had liver transplantation after coronary artery bypass grafting (CABG). The liver disease in most of the patients was a consequence of hepatitis C resulting from blood transfusions at the time of CABG.