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Desmopressin tablet treatment: factors influencing gastrointestinal absorption
S Rittig1, A R Jensen, K T Jensen
1Research Laboratory of Nephrology and Hypertension, Skejby Hospital, University Hospital of Aarhus, Denmark.
Scandinavian Journal of Urology and Nephrology. Supplementum
|January 1, 1997
Abstract:
The effect of food ingestion on the gastrointestinal absorption and antidiuretic action of oral desmopressin (Minirin, DDAVP) was assessed in 16 healthy volunteers, aged 20-35 years. The gastrointestinal absorption of desmopressin was reduced and delayed if administered with or 90 minutes after a meal, but this did not influence the antidiuretic action of the drug, at least for the first 3 hours following desmopressin administration.