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Hoigne's syndrome, kindling, and panic disorder
A Araszkiewicz1, J K Rybakowski
1Department of Psychiatry, Medical Academy, Bydgoszcz, Poland.
Abstract:
A review of Hoigne's syndrome (HS) is presented, and 47 cases of putative procaine penicillin-induced HS are discussed within the context of kindling models of human psychopathology. Sixty percent of the individuals with HS in our retrospective study reported a lifetime history of panic disorder. The risk factors and causal relationships among repeated injection of procaine penicillin, HS, and anxiety disorders, particularly panic disorder, require further investigation.
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