Related Experiment Videos
IDDM incidence in a multiracial population. The Hawaii IDDM Registry, 1980-1990
S L Patrick1, J K Kadohiro, S H Waxman
1World Health Organization Collaborating Center for Diabetes Research, Registries and Training, Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania, USA. scp3@wonder.em.cdc.gov
Diabetes Care
|June 1, 1997
Summary
The Hawaii IDDM Registry found the lowest incidence of insulin-dependent diabetes mellitus (IDDM) in U.S. children. Part-Hawaiian children had 2.5 times higher IDDM rates than Caucasians, with temporal increases possibly linked to a pandemic.
Area of Science:
- Epidemiology
- Pediatric Endocrinology
- Public Health
Background:
- The Hawaii IDDM Registry was established to investigate IDDM incidence in children on Oahu.
- Hawaii's diverse population offers a unique setting to study migration's impact on IDDM.
- Previous studies on IDDM incidence in multiracial populations are limited.
Purpose of the Study:
- To determine the incidence rate of IDDM in children under 15 years on Oahu from 1980 to 1990.
- To analyze IDDM incidence by race and ethnicity.
- To examine temporal trends in IDDM incidence.
Main Methods:
- Retrospective hospital chart review and physician surveys were used for data collection.
- Inclusion criteria: age 0-14 at diagnosis, Oahu residency; military dependents excluded.
- Denominator data were compared from two sources to ensure accuracy.
Main Results:
- 113 new-onset IDDM cases were identified with 97% ascertainment.
- Annual incidence rate ranged from 7.04-7.61 per 100,000.
- Significant ethnic variations observed: Part-Hawaiian (15.34-16.58), Caucasian (6.21-6.71), Filipino (3.66-3.96), Japanese (2.85-3.08).
Conclusions:
- Hawaii reported the lowest IDDM incidence in U.S. children.
- Part-Hawaiian children exhibited 2.5 times higher IDDM incidence than Caucasian children.
- Temporal fluctuations correlated with a mid-1980s IDDM pandemic.