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Fine needle aspiration biopsy in hepatic Echinococcus multilocularis
M A Ciftçioğlu1, M I Yildirgan, M N Akçay
1Department of Pathology, School of Medicine, Atatürk University, Erzurum, Turkey.
Acta Cytologica
|May 1, 1997
Summary
Fine needle aspiration biopsy (FNAB) effectively diagnoses hepatic Echinococcus multilocularis by identifying characteristic PAS-positive structures and necrosis. These cytologic findings provide essential criteria for diagnosing this parasitic liver infection.
Area of Science:
- Hepatology
- Parasitology
- Diagnostic Cytopathology
Background:
- Hepatic Echinococcus multilocularis is a serious parasitic infection.
- Accurate and early diagnosis is crucial for effective management.
- Fine needle aspiration biopsy (FNAB) is a minimally invasive diagnostic tool.
Purpose of the Study:
- To identify and characterize the specific findings of FNAB in cases of hepatic Echinococcus multilocularis.
- To establish diagnostic criteria for FNAB in hepatic E. multilocularis.
Main Methods:
- FNAB and tru-cut liver biopsy were performed on 14 patients with hepatic E. multilocularis.
- Cytologic smears were stained with May-Grünwald-Giemsa and PAS.
- Tissue sections were stained with HE and PAS.
Main Results:
- Tissue sections showed PAS-positive, homogeneous, thin cystic structures and coagulative necrosis.
- Cytologic smears revealed necrotic material, PAS-positive hyaline cuticular structures, and mucoid globules.
- Foreign body-type giant cells were observed in some cases in both smears and tissue.
Conclusions:
- Specific cytologic features observed in FNAB are fundamental for diagnosing hepatic Echinococcus multilocularis.
- FNAB can reliably detect characteristic pathological findings of E. multilocularis in the liver.