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Updated: Jul 29, 2026

A Computational Modeling Approach to Investigate the Influence of Hyperthermia on the Tumor Microenvironment
Published on: December 1, 2023
Temperature distributions during thermoradiotherapy: a sensitivity study with a transient numerical model of the
D T Tompkins1, S A Klein, R A Steeves
1Department of Engineering Experiment Station, University of Wisconsin-Madison 53703, USA.
Abstract:
An approach to the treatment of medium-sized choroidal melanomas combines radiation with ferromagnetic hyperthermia. The study herein discusses results with a numerical thermal model of a choroidal melanoma in the rabbit eye as treated with episcleral, thermoradiotherapy plaques. The sensitivity of a temperature-dependent blood perfusion model is investigated.
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