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Retinal examinations in infants after extracorporeal membrane oxygenation

M M Varn1, M L Donahue, R A Saunders

  • 1N. Edgar Miles Center for Pediatric Ophthalmology, Medical University of South Carolina, Charlston 29425-2236, USA.

Insights

Routine ophthalmic examinations in infants after extracorporeal membrane oxygenation (ECMO) revealed no clinically significant retinal findings. This suggests post-ECMO eye screenings may not be necessary, reducing infant stress.

Area of Science:

  • Ophthalmology
  • Neonatal Medicine
  • Critical Care

Background:

  • Ocular abnormalities can occur in infants following extracorporeal membrane oxygenation (ECMO).
  • Routine ophthalmic examinations are recommended for infants undergoing ECMO.
  • Previous studies suggest a potential link between ECMO and vision-threatening eye conditions.

Purpose of the Study:

  • To evaluate the necessity of routine ophthalmic examinations in infants post-ECMO.
  • To determine the incidence of clinically significant retinal findings in infants after ECMO.
  • To assess the cost-effectiveness and impact of post-ECMO eye screenings.

Main Methods:

  • Retrospective review of medical records for infants treated with ECMO.
  • Analysis of ophthalmic examination data performed before or immediately after hospital discharge.
  • Examinations were conducted similarly to retinopathy of prematurity screening protocols.

Main Results:

  • 171 infants (342 eyes) were included in the study.
  • 88% of eyes (302/342) showed normal fundus examinations.
  • Abnormal retinovascular findings, when present, were not vision-threatening and required no treatment.

Conclusions:

  • No clinically important retinal findings were identified in infants screened post-ECMO.
  • Routine dilated fundus examinations after ECMO may not be cost-effective.
  • Post-ECMO eye screenings can impose unnecessary stress on infants.
Abstract

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