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Postprandial changes in superoxide dismutase activity in subjects with Gilles de la Tourette syndrome and controls
A N Saghir1, H Rickards, H S Pall
1Department of Neurology, Queen Elizabeth Hospital, Edgbaston, Birmingham, United Kingdom.
Experimental Neurology
|April 1, 1997
Abstract:
Erythrocyte measures of copper-zinc superoxide dismutase (CuZnSOD) were performed on 11 subjects with a clinical diagnosis of Gilles de la Tourette syndrome (GTS) and 6 healthy controls at specified intervals throughout the day. There were no significant differences between GTS subjects and controls but in both subjects and controls there was a significant increase in SOD, 75 min postprandially, which decreased to baseline 135 min postprandially. This has implications for the timing of biological samples in future studies of SOD. Possible reasons for the increase are discussed.