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Related Experiment Videos

Third ventricle: size and appearance in normal fetuses through gestation

B S Hertzberg1, M A Kliewer, K S Freed

  • 1Department of Radiology, Duke University Medical Center, Durham, NC 27710, USA.

Radiology
|June 1, 1997
PubMed
Summary

The fetal third ventricle is visible in most second and third-trimester scans. Its appearance changes throughout gestation, with a width over 3.5 mm indicating potential abnormality.

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Area of Science:

  • Fetal Medicine
  • Neuroimaging
  • Developmental Biology

Background:

  • The fetal third ventricle's normal appearance and size are crucial for prenatal diagnosis.
  • Understanding its typical development aids in identifying potential abnormalities.

Purpose of the Study:

  • To establish the normative size and appearance of the fetal third ventricle.
  • To define imaging characteristics across gestational ages.

Main Methods:

  • Prospective assessment of 441 normal fetuses in the second and third trimesters.
  • Categorization of fetuses into six gestational age groups.
  • Analysis of third ventricle size and configuration.

Main Results:

  • The third ventricle was visualized in 98.9% of fetuses.

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  • Configurations varied: single echogenic line (38.9%), parallel lines (55.2%), divergent lines (4.8%).
  • Average width remained ~1 mm from 12-28 weeks, then increased to a maximum of 1.9 mm.

    • Conclusions:

    • The fetal third ventricle is reliably imaged during the second and third trimesters.
    • Its size and configuration undergo significant evolution during gestation.
    • A third ventricle width exceeding 3.5 mm warrants concern for fetal abnormality.