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Chlamydia trachomatis growth stimulates interleukin 8 production by human monocytic U-937 cells
A Bianchi1, C Dosquet, S Henry
1Laboratoire de Bactériologie-Virologie-Hygiène, Hôpital Saint-Louis,Université Paris VII, France.
Infection and Immunity
|June 1, 1997
Abstract:
Growth of Chlamydia trachomatis serotypes L2 and L3 in a human monocytic cell line, U-937, increased the rate of interleukin 8 (IL-8) release 100-fold. Heat-killed chlamydiae induced a 10-fold-lower level of production of IL-8. IL-8 may play an important role in the inflammatory reaction to chlamydial infection.