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Updated: Jul 9, 2026

Measuring Bacterial Load and Immune Responses in Mice Infected with Listeria monocytogenes
Published on: August 9, 2011
Isolation and characterization of a Listeria monocytogenes mutant strain hyperproducing virulence factors
S Ermolaeva1, N Varfolomeeva, Y Belyi
1Gamaleya Research Institute of Epidemiology and Microbiology, Moscow, Russia. sveta@ermolaeva.msk.su
Abstract:
A mutant strain characterized by hyperproduction of a number of cell wall and supernatant proteins was isolated after N'methyl-N'-nitro-N-nitrosoguanidine treatment of Listeria monocytogenes strain NCTC10527. Several of these proteins were identified as virulence factors. When a wild-type strain was grown in the presence of activated charcoal it was shown to exhibit the same protein pattern as the isolated mutant.
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