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Kinetics of trans- and cis-resveratrol (3,4',5-trihydroxystilbene) after red wine oral administration in rats
A A Bertelli1, L Giovannini, R Stradi
1Institute of Anatomy, University of Milan, Italy.
International Journal of Clinical Pharmacology Research
|January 1, 1996
Abstract:
Kinetics of trans- and cis-resveratrol (3,4',5-trihydroxystilbene), a natural compound from grape products, have been evaluated in rats after oral administration of red wine. Resveratrol concentrations were measured in plasma, heart, liver and kidneys. Tissue concentrations showed a significant cardiac bioavailability and strong affinity for liver and kidneys.