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Related Experiment Videos

Orderly oriented wire mesh: a novel porous coating

S H Naidu1, M J Moulton, J M Cuckler

  • 1Department of Orthopedic Surgery, Pennsylvania State University, Hershey Medical Center, Hershey, USA.

Orthopedics
|May 1, 1997
PubMed
Summary

A novel porous coating, orderly oriented wire mesh (OOWM), matches porous beads for bone ingrowth and stability. The 25 x 25 single layer OOWM showed superior early stability in an in vivo model.

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Area of Science:

  • Biomaterials Science
  • Orthopedic Surgery
  • Tissue Engineering

Background:

  • Commercially available porous beads and fiber metal mesh are used for bone ingrowth.
  • There is a need for alternative porous coatings with enhanced stability and bone integration.

Purpose of the Study:

  • To develop and evaluate a new porous coating, orderly oriented wire mesh (OOWM).
  • To compare the in vivo bone ingrowth and mechanical stability of OOWM with porous beads.

Main Methods:

  • Rectangular plugs with porous beads and four OOWM configurations were implanted into canine femoral condyles.
  • Mechanical pullout strength was assessed at 4, 8, and 12 weeks postimplantation.
  • An in vivo unloaded model was utilized.

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Main Results:

  • Porous beads and the simplest OOWM configuration demonstrated equivalent mechanical stability at 12 weeks.
  • The 25 x 25 single layer OOWM configuration exhibited significantly greater stability at 4 weeks compared to other OOWM types.
  • Early bone ingrowth and stability were observed with OOWM.

Conclusions:

  • Orderly oriented wire mesh (OOWM) is a viable alternative to porous beads for orthopedic applications.
  • OOWM facilitates early bone ingrowth and provides mechanical stability in an unloaded in vivo environment.
  • Specific OOWM configurations, like the 25 x 25 single layer, offer enhanced early stability.