Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Tissue microdialysis: practical and theoretical aspects]

M Cimmino1, A Géloën

  • 1Laboratoire de Physiologie des Régulations Energétiques, Cellulaires et Moléculaires, UMR 5578 CNRS/Faculté de Médecine, Lyon Nord, France.

Diabetes & Metabolism
|April 1, 1997
PubMed
Summary

This review details in vivo microdialysis techniques for peripheral tissue research. It offers practical guidance on probe selection, perfusion, and data analysis for metabolite monitoring and drug delivery.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The use of Fibrin Sealants in Reducing Drain Output in Abdominoplasty: Is it Useful?

JPRAS open·2024
Same author

Hypothesis: Fever control, a niche for alpha-2 agonists in the setting of septic shock and severe acute respiratory distress syndrome?

Temperature (Austin, Tex.)·2018
Same author

Metabolic effects in mice of cream processing: Direct ultra-high-temperature process lowers high-fat-induced adipose tissue inflammation.

Journal of dairy science·2018
Same author

Metabolic effects in mice of cream formulation: Addition of both thickener and emulsifier does not alter lipid metabolism but modulates mucus cells and intestinal endoplasmic reticulum stress.

Journal of dairy science·2018
Same author

Overexpression of chromatin assembly factor-1/p60 predicts biological behaviour of laryngeal carcinomas.

Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale·2017
Same author

Cytotoxicity control of silicon nanoparticles by biopolymer coating and ultrasound irradiation for cancer theranostic applications.

Nanotechnology·2017

Area of Science:

  • Biomedical Engineering
  • Neuroscience
  • Pharmacology

Context:

  • Microdialysis is a key technique for studying peripheral tissues.
  • It enables monitoring of extracellular metabolites and small molecules.
  • Allows local delivery of active agents into tissues.

Purpose:

  • To provide a practical guide to in vivo microdialysis.
  • Discuss theoretical aspects like probe efficiency and recovery.
  • Equip researchers with tools for mastering tissular microdialysis.

Summary:

  • This review covers practical aspects of microdialysis, including probe types, molecular cut-off, and perfusion rates.
  • Theoretical considerations such as probe efficiency, recovery, and metabolism quantification are discussed.

Related Experiment Videos

  • The aim is to facilitate researchers' understanding and application of in vivo microdialysis.

    • Impact:

    • Enhances the study of peripheral tissue physiology and pathology.
    • Facilitates drug development and delivery research.
    • Provides a foundation for advanced research in metabolomics and pharmacology.