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Updated: Aug 7, 2026

Invasive Hemodynamic Characterization of the Portal-hypertensive Syndrome in Cirrhotic Rats
Published on: August 1, 2018
[Complications of transcutaneous transhepatic endovascular interventions in patients with portal hypertension]
Insights
Endovascular treatment for portal hypertension showed a 23.4% complication rate, including bleeding and thrombosis. Mortality was 2.5%, with complications often linked to underlying liver disease and high portal pressure.
Area of Science:
- Interventional Radiology
- Hepatology
- Vascular Surgery
Background:
- Portal hypertension is a serious condition often leading to life-threatening complications.
- Effective management strategies are crucial for improving patient outcomes.
Purpose of the Study:
- To analyze the outcomes of endovascular treatment in patients with portal hypertension.
- To identify the types and rates of complications associated with these procedures.
Main Methods:
- Retrospective analysis of 196 patients undergoing endovascular treatment for portal hypertension.
- Evaluation of complication rates, including intra-abdominal bleeding and portal vein thrombosis.
- Assessment of procedure-related mortality.
Main Results:
- A total complication rate of 23.4% was observed.
- Serious complications included intra-abdominal bleeding (2.5%) and portal vein thrombosis (2.1%).
- Procedure-related mortality was 2.5%.
Conclusions:
- Endovascular treatment for portal hypertension carries a significant complication risk.
- Complications are frequently associated with the severity of underlying liver disease, ascites, high portal pressure, and coagulopathy.
Abstract:
Results of endovasal treatment of 196 patients with portal hypertension and its complications are analysed. The total rate of complications is 23.4%, the most serious of them were intraabdominal bleeding (2.5%), portal vein thrombosis (2.1%). The rate of mortality, related to the complications of transhepatic procedures, was 2.5%. The majority of the complications were specific to the character of the disease: liver cirrhosis, ascites, high portal pressure, coagulating system disorders.
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