[The biochemical correlates of the individual typological characteristics of rat behavior]

The review of data (results of the authors' investigations and data from the literature) concerning neurochemical correlates of individual behavior in rats is presented. The "emotional resonance" test was used for behavioral selection of rats. Individual behavior in this test is related to the differences in free radical mediated processes, membrane lipid content, nitric oxide synthase activity and cAMP pattern in cerebral macrostructures. Behavior-related differences were revealed in intact animals, and in response to environmental factors. These differences depend on age; they may be global or specific for selected brain regions and/or related to interhemispheric lateralization of biochemical parameters.