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[Outbreak of meningitis caused by echovirus type 30]
M I López Alcalá1, M Rodríguez Priego, D de la Cruz Morgado
1Hospital Infanta Margarita, Cabra, Córdoba.
Objectives:
In the cold months of 1994-1995, we detected in our hospital an epidemic outbreak of acute enteroviral meningitis caused by echovirus type 30 (Echo 30). Until now, these outbreaks of viral epidemics had not been detected in Spain.
Patients And Methods:
We reviewed retrospectively 46 clinical histories of patients who were admitted to our hospital between September 1994 and January 1995 with the diagnosis of acute lymphocytic meningitis, analyzing the clinical outbreak, epidemiological and laboratory characteristics, and how the outbreak spread.
Results:
Regarding the patients, there was a prevalence in males, with an average age of 6 years and a range of 2 to 13 years of age. The most constant symptom was severe frontal headache, with signs of meningitis in only 50% of the cases. In the CSF, we found a predominance of PMN in the differential cell count in 63% of the cases, with the time of evolution before spinal puncture less than 24 hours in the majority of the patients. Viral cultures were performed on CSF, stool and throat scrapings in 16 patients with Echo 30 being isolated in 15 cases, which suggests 32.6% of the total cases.
Conclusions:
We detected in our environment an epidemic outbreak of viral meningitis caused by an agent not found previously in Spain, which presented epidemiological, clinical and laboratory characteristics similar to those reported in the literature. Its appearance during the cold months contrasts to what normally occurs.
Insights
An epidemic of enteroviral meningitis caused by echovirus type 30 (Echo 30) occurred in Spain during 1994-1995. This viral meningitis outbreak presented with headache and meningitis signs in 50% of patients.
Area of Science:
- Virology
- Epidemiology
- Infectious Diseases
Context:
- An epidemic outbreak of acute enteroviral meningitis occurred in Spain during the cold months of 1994-1995.
- This outbreak was caused by echovirus type 30 (Echo 30), a virus not previously detected in Spain.
Purpose:
- To describe the clinical, epidemiological, and laboratory characteristics of an echovirus type 30 outbreak.
- To analyze the spread and presentation of this novel viral meningitis epidemic in Spain.
Summary:
- A retrospective review of 46 patients with acute lymphocytic meningitis revealed a prevalence in males aged 2-13 years.
- Severe frontal headache was the most common symptom; meningitis signs were present in 50% of cases.
- Echovirus 30 was isolated from 15 out of 16 patients tested (32.6% of total cases), with PMN predominance in CSF in 63%.
Impact:
- This study identified a new viral meningitis agent in Spain, highlighting its distinct epidemiological and clinical features.
- The findings contribute to understanding enteroviral meningitis outbreaks and their emergence in new geographical regions.
- The occurrence during colder months contrasts with typical patterns, suggesting unique environmental or host factors may be involved.