Related Experiment Videos
Frequency of HLA-B27 subtypes in a Danish population and in Danish patients with ankylosing spondylitis
J Baech1, S Schmidt-Olsen, R Steffensen
1Regional Centre for Blood Transfusion and Clinical Immunology, Aalborg Hospital, Denmark.
Tissue Antigens
|May 1, 1997
Abstract:
Polymerase chain reaction in combination with sequence-specific oligonucleotide probes were used to analyze nine HLA-B27 subtypes among 51 healthy HLA-B27 positive Danish blood donors and 30 Danish HLA-B27 positive patients with ankylosing spondylitis (AS). In the group of healthy Danes we found two subtypes, B*2705 (90.2%) and B*2702 (9.8%), however, among the AS patients only the B*2705 subtype was detected. We did not find a significant evidence for associations between AS and a particular HLA-B27 subtype in a Danish population.