Fibrous dysplasia

Area of Science:

• Orthopedics
• Pathology

Background:

• Fibrous dysplasia (FD) is a rare bone disorder.
• Current research focuses on pathogenesis, endocrinopathies, pigmentation, and malignant transformation.
• Orthopedic aspects include diagnosis and management of complications.

Purpose of the Study:

• To provide an overview of the spectrum and natural history of fibrous dysplasia.
• To highlight the orthopedic management of fibrous dysplasia.

Main Methods:

• Review of clinical experience with over 50 patients.
• Diagnosis aided by biopsy.
• Conservative surgical treatment for monostotic lesions.

Main Results:

• Diagnosis of fibrous dysplasia is straightforward with biopsy.
• Experience gained in managing fractures and deformities in polyostotic fibrous dysplasia.
• Conservative surgical approaches are recommended for monostotic lesions.

Conclusions:

• Understanding the spectrum and natural history of fibrous dysplasia is crucial for management.
• Orthopedic care involves straightforward diagnosis and management of complications.
• Conservative treatment and experience are key in managing fibrous dysplasia patients.