Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Happy animals make good science

T Poole1

  • 1Universities Federation for Animal Welfare, Potters Bar, Hertfordshire, UK.

Laboratory Animals
|April 1, 1997
PubMed
Summary
This summary is machine-generated.

Ensuring laboratory animal happiness is crucial for reliable scientific outcomes. Compromised animal well-being leads to physiological abnormalities, potentially invalidating research findings and raising ethical concerns.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

ROTEM<sup>®</sup> sigma reference range validity.

Anaesthesia·2019
Same author

Frequency dependence of surface acoustic wave swimming.

Journal of the Royal Society, Interface·2019
Same author

Acoustoelectric Current in Graphene Nanoribbons.

Scientific reports·2017
Same author

Transfer of the virulence-associated protein a-bearing plasmid between field strains of virulent and avirulent Rhodococcus equi.

Journal of veterinary internal medicine·2014
Same author

Conjugative plasmid transfer between Salmonella enterica Newport and Escherichia coli within the gastrointestinal tract of the lesser mealworm beetle, Alphitobius diaperinus (Coleoptera: Tenebrionidae).

Poultry science·2009
Same author

A short gamma-ray burst apparently associated with an elliptical galaxy at redshift z = 0.225.

Nature·2005
Same journal

Standardized surgical access to the porcine temporomandibular joint: Anatomical basis for translational research.

Laboratory animals·2026
Same journal

Development of animal use in experiments: a brief historical overview.

Laboratory animals·2026
Same journal

The reduction potential of diet board feeding-survival and clinical chemistry of group-housed Sprague Dawley rats in a 24-month study.

Laboratory animals·2026
Same journal

Advancing the 3Rs? Researchers' perspectives on institutional facilitation in Switzerland - Part 2: executive facilitation.

Laboratory animals·2026
Same journal

Recognition of pain and distress.

Laboratory animals·2026
Same journal

Strengthening animal welfare: monitoring humane endpoints in a rat model of mammary tumorigenesis undergoing a ladder resistance training protocol.

Laboratory animals·2026
See all related articles

Area of Science:

  • Animal research ethics
  • Laboratory animal science
  • Scientific methodology

Background:

  • Animal welfare is increasingly recognized as a critical factor in research.
  • Compromised psychological well-being in animals can lead to physiological and immunological abnormalities.
  • Such abnormalities may impact the validity and reproducibility of scientific experiments.

Purpose of the Study:

  • To explore the impact of animal psychological well-being on scientific results.
  • To highlight the importance of considering animal welfare in experimental design.
  • To advocate for the ethical treatment of animals in research settings.

Main Methods:

  • Literature review of existing evidence on animal well-being and its effects on research.
  • Analysis of the relationship between animal physiology/behavior and experimental outcomes.

Related Experiment Videos

  • Ethical considerations in laboratory animal care and use.
  • Main Results:

    • Evidence suggests a link between compromised animal well-being and abnormal physiological/immunological states.
    • Experiments using animals with poor welfare may yield unreliable or irreproducible results.
    • Maintaining normal physiology and behavior in animals is essential for good science.

    Conclusions:

    • The psychological well-being of laboratory animals is paramount for both scientific integrity and ethical research practices.
    • Veterinarians, animal technicians, and scientists must prioritize animal welfare.
    • Addressing animal welfare ensures more accurate and meaningful scientific discoveries.