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Pregnancy and birth after intracytoplasmic sperm injection with totally immotile sperm recovered from the ejaculate
A Barros1, M Sousa, C Oliveira
1Laboratory of Medical Genetics, Faculty of Medicine, University of Porto, Portugal.
Objective:
To report the birth of two healthy children after intracytoplasmic sperm injection (ICSI) with totally immotile spermatozoa recovered from the ejaculate.
Design:
Retrospective case report.
Setting:
University-based hospital.
Patient(S):
Four couples in whom spermatozoa recovered from the ejaculate were totally immotile but presented normal vitality scores.
Intervention(S):
Therapeutical IVF-ET attempts coupled with ICSI.
Main Outcome Measure(S):
Fertilization and pregnancy results after ICSI.
Results:
With random sperm injection, 19 of the 36 injected oocytes showed normal fertilization and cleavage. One of four patients had a twin pregnancy that resulted in birth of two healthy children.
Conclusion(S):
In cases in which totally immotile ejaculated sperm present normal vitality scores, normal clinical outcomes can be achieved by using the usual random sperm selection during conventional ICSI.