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Ménétrier's disease: a new variant with duodenal involvement
1Department of Medicine, Chang Gung Memorial Hospital, Taipei, Taiwan, Republic of China.
The American Journal of Gastroenterology
|June 1, 1997
Summary
Ménétrier
Area of Science:
- Gastroenterology
- Pathology
Background:
- Ménétrier's disease is a rare condition causing hypertrophic gastropathy.
- It typically affects the stomach's body and fundus, presenting with giant rugae and hypoalbuminemia.
Observation:
- A 74-year-old man presented with dyspepsia, hypoalbuminemia, and weight loss.
- Gastroscopy revealed diffuse polypoid lesions throughout the stomach and proximal duodenum.
Findings:
- Histology confirmed Ménétrier's disease involving both the stomach and duodenum, an unusual presentation.
- The patient experienced complete clinical, endoscopic, and pathological resolution after famotidine treatment.
Implications:
- This case suggests Ménétrier's disease may present with duodenal involvement.
- The patient's presentation may represent a variant of Ménétrier's disease with a favorable prognosis.
- Famotidine therapy showed efficacy in treating this rare condition.