Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Movement disorders in Japanese encephalitis

U K Misra1, J Kalita

  • 1Department of Neurology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India. ukmisra@sgpgi.ren.nic.in

Journal of Neurology
|May 1, 1997
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Complications of tuberculous meningitis and their effect on outcome in a tertiary care cohort.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease·2020
Same author

Impaired Autophagy Flux is Associated with Proinflammatory Microglia Activation Following Japanese Encephalitis Virus Infection.

Neurochemical research·2020
Same author

Hypovolemia due to cerebral salt wasting may contribute to stroke in tuberculous meningitis.

QJM : monthly journal of the Association of Physicians·2018
Same author

Spectrum of hyperosmolar hyperglycaemic state in neurology practice.

The Indian journal of medical research·2018
Same author

A study of atrial and brain natriuretic peptides in tuberculous meningitis and acute encephalitis.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease·2018
Same author

Alpha coma in Japanese encephalitis.

Neurology India·2018

Movement disorders are common in Japanese encephalitis (JE). Thalamic involvement, often bilateral, is frequently observed and may cause these neurological symptoms.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Neuroimaging

Background:

  • Movement disorders are known complications of Japanese encephalitis (JE) but lack systematic analysis.
  • Understanding the neuroanatomical basis of these disorders is crucial for patient management.

Purpose of the Study:

  • To systematically analyze movement disorders in JE patients.
  • To correlate clinical movement disorders with radiological findings.

Main Methods:

  • Analysis of 14 Japanese encephalitis patients with movement disorders.
  • Clinical assessment of extrapyramidal signs and dyskinesias.
  • Cranial CT, MRI, and SPECT imaging to evaluate brain involvement.
  • Serological confirmation of JE infection via IgG antibodies.

Related Experiment Videos

Main Results:

  • All patients exhibited extrapyramidal signs post-coma, including hypokinesia and facial masking.
  • Thalamic involvement was detected in 10 patients via CT and all 9 patients via MRI, often bilateral.
  • MRI revealed additional involvement in the lentiform nucleus, midbrain, pons, and cerebellum.
  • SPECT showed bilateral thalamic hypoperfusion in all examined patients.

Conclusions:

  • Movement disorders are a frequent manifestation of Japanese encephalitis.
  • Thalamic involvement, isolated or combined with basal ganglia or midbrain lesions, is a primary cause of JE-associated movement disorders.